CSO at Thiomatrix Forschungs- Beratungs GmbH
Andreas Bernkop-Schnürch is a leading scientist in the field of drug delivery focusing on mucoadhesive polymers such as in particular thiomers, non-invasive peptide delivery systems and nanoemulsions.
He is chairman at the Department of Pharmaceutical Technology at the University of Innsbruck, Austria and CSO of the drug delivery company ThioMatrix GmbH. He has published more than 500 reseach and review articles.
Title: Advanced nanoemulsions: Key to high bioavailability of class 3 drugs
- Improving membrane permeability of charged class 3 drugs
- The destabilizing effect of endogenous counterions in the GI-tract and the concept of hydrophobic ion-pairing
- Hydrophobic ion-pairs reach consequently the absorption membrane in intact form providing comparatively much higher drug absorption
- Evidence for the potential of this novel game changing technology has already been provided by various in vivo studies showing a 10- up to 20-fold improved oral bioavailability of different types of class 3 drugs