Eva-Maria Knoch

Senior Scientist I at AbbVie

Eva-Maria Knoch is a Senior Scientist in NBE Drug Product Development at AbbVie Ludwigshafen. In 2013 and 2014 she was running her PostDoctoral studies at AbbVie, focused in Drug Product Development, NBE Formulation and Process Sciences. Since June 2014 she is working as a Senior Scientist at AbbVie, focusing in Drug Product Development, NBE Formulation Sciences.


Title: The challenge of low volumes - Implementation of low-consumption analytical methods for automated high throughput formulation screenings of biologics

  • Establishment of an automated high-throughput formulation screening platform offers the advantage to generate huge and homogeneous datasets that enable a profound understanding of the behavior of a new molecule, while minimizing resource demands, both for drug substance and personal
  • The analytical methods that are commonly available often require high volumes
  • The introduction to alternative methods at low-volume consumption for profound characterization of the formulation as well as the approach to systematically perform formulation screenings