{"id":35120,"date":"2020-11-16T15:03:13","date_gmt":"2020-11-16T15:03:13","guid":{"rendered":"https:\/\/www.biotechpharmasummit.com\/?page_id=35120"},"modified":"2021-03-18T11:55:20","modified_gmt":"2021-03-18T11:55:20","slug":"christa-noehammer","status":"publish","type":"page","link":"https:\/\/www.biotechpharmasummit.com\/index.php\/cdx-biomarkers-biobanking-2021-speakers\/christa-noehammer\/","title":{"rendered":"Christa Noehammer"},"content":{"rendered":"<div class=\"vgblk-rw-wrapper limit-wrapper\">\n<h2>Dr. Christa Noehammer<\/h2>\n<h4>Senior Scientist at AIT (Austrian Institute of Technology)<\/h4>\n\t<p>Christa Noehammer works as Senior Scientist at the Austrian Institute of Technology where she has been heading the Molecular Medicine research unit for several years. Holding a master degree in Microbiology and a PhD in Biochemistry she has been working in the microarray field since 1999 being involved in the design, production and data analysis of various microarray types thereby mainly focusing on minimally invasive biomarker discovery for cancer diagnostics.<\/p>\n<p>The last couple of years Dr. Noehammer has been very much involved in the setup of sampling &#8211; and biomarker isolation protocols as well as high throughput biomarker technologies for saliva diagnostics. Recently she is having a focus on small RNA sequencing from saliva- and plasma-derived exosomes which she e.g. took advantage of in a project aiming for the discovery and verification of exosomal epigenetic biomarkers for early diagnosis of type 2 diabetes.<\/p>\n\t\t\t\t\t\t\t<img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.biotechpharmasummit.com\/wp-content\/uploads\/2020\/11\/Noehammer_Christa_Ait_BioTech_Pharma_Summit_2021_Profile_1.jpg\" alt=\"Noehammer_Christa_Ait_BioTech_Pharma_Summit_2021_Profile_1\" itemprop=\"image\" height=\"1224\" width=\"820\" title=\"Noehammer_Christa_Ait_BioTech_Pharma_Summit_2021_Profile_1\" onerror=\"this.style.display='none'\" sizes=\"(max-width: 768px) 100vw, 100vw\" srcset=\"data:image\/svg+xml;utf8,<svg%20xmlns=&quot;http:\/\/www.w3.org\/2000\/svg&quot;%20viewBox=&quot;0%200%20820%201224&quot;%20height=&quot;1224px&quot;%20width=&quot;820px&quot;\/>&#8221; data-srcset=&#8221;https:\/\/www.biotechpharmasummit.com\/wp-content\/uploads\/2020\/11\/Noehammer_Christa_Ait_BioTech_Pharma_Summit_2021_Profile_1.jpg 820w, https:\/\/www.biotechpharmasummit.com\/wp-content\/uploads\/2020\/11\/Noehammer_Christa_Ait_BioTech_Pharma_Summit_2021_Profile_1-201&#215;300.jpg 201w, https:\/\/www.biotechpharmasummit.com\/wp-content\/uploads\/2020\/11\/Noehammer_Christa_Ait_BioTech_Pharma_Summit_2021_Profile_1-686&#215;1024.jpg 686w, https:\/\/www.biotechpharmasummit.com\/wp-content\/uploads\/2020\/11\/Noehammer_Christa_Ait_BioTech_Pharma_Summit_2021_Profile_1-768&#215;1146.jpg 768w, https:\/\/www.biotechpharmasummit.com\/wp-content\/uploads\/2020\/11\/Noehammer_Christa_Ait_BioTech_Pharma_Summit_2021_Profile_1-630&#215;940.jpg 630w, https:\/\/www.biotechpharmasummit.com\/wp-content\/uploads\/2020\/11\/Noehammer_Christa_Ait_BioTech_Pharma_Summit_2021_Profile_1-420&#215;627.jpg 420w, https:\/\/www.biotechpharmasummit.com\/wp-content\/uploads\/2020\/11\/Noehammer_Christa_Ait_BioTech_Pharma_Summit_2021_Profile_1-315&#215;470.jpg 315w&#8221;>\t\t\t\t\t\t\t\n<h3>\n\tTitle: Epigenetic biomarkers for Type 2 Diabetes from plasma &#8211; and saliva derived extracellular vesicles\n\t<\/h3>\n\t<div class=\"su-expand su-expand-collapsed su-expand-link-style-default\" data-height=\"200\"><div class=\"su-expand-content su-u-trim\" style=\"color:#333333;max-height:200px;overflow:hidden\">\n<ul>\n<li>Extracellular vesicles (EVs) were isolated from cell-free saliva and plasma of a patient cohort comprising diabetic, pre-diabetic, gestational diabetic and healthy individuals. EV-derived DNA and RNA was used for epigenetic biomarker discovery applying genome-wide DNA methylation profiling, small RNA sequencing respecitively.<\/li>\n<li>A comprehensive comparison of small RNA Seq library approaches was performed before selecting the most suitable approach for the small RNA biomarker discovery study done in plasma and saliva samples of a diabetic patient cohort. miRNA candidate markers were verified via qPCR in indepedent plasma and saliva samples.<\/li>\n<li>Whole genome DNA methylation profiling was successfully performed from saliva-EV derived DNA and potential biomarker candidates identified. Methylation sensitive restriction enzyme (MSRE)-based qPCR was applied for DNA methylation biomarker verification.<\/li>\n<\/ul>\n<\/div><div class=\"su-expand-link su-expand-link-more\" style=\"text-align:left\"><a href=\"javascript:;\" style=\"color:#0088FF;border-color:#0088FF\"><span style=\"border-color:#0088FF\">Show more<\/span><\/a><\/div><div class=\"su-expand-link su-expand-link-less\" style=\"text-align:left\"><a href=\"javascript:;\" style=\"color:#0088FF;border-color:#0088FF\"><span style=\"border-color:#0088FF\">Show less<\/span><\/a><\/div><\/div>\n<h4>\n\t\t\t<a href=\"#\" title=\"On the Web\" target=\"_self\" rel=\"noopener noreferrer\">\n\tOn the Web\n\t\t\t<\/a>\n\t<\/h4>\n\t<p><a href=\"https:\/\/www.ait.ac.at\/\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.ait.ac.at\/<\/a><\/p>\n<h4>\n\t\t\t<a href=\"#\" title=\"On LinkedIn\" target=\"_self\" rel=\"noopener noreferrer\">\n\tOn LinkedIn\n\t\t\t<\/a>\n\t<\/h4>\n\t<p><a href=\"https:\/\/www.linkedin.com\/in\/christa-noehammer-0252a033\/\" target=\"_blank\" rel=\"noopener noreferrer\">Visit Profile<\/a><\/p>\n<h4>\n\tPast Presentations\n\t<\/h4>\n<h5>\n\t1. CDx &amp; Biomarkers Summit 2019 &#8211; Exosome-derived epigenetic biomarkers for saliva diagnostics\n\t<\/h5>\n\t<a href=\"https:\/\/www.biotechpharmasummit.com\/wp-content\/uploads\/2020\/08\/Cdx-Biomarkers-2019_Porto_Noehammer_2.pdf\" target=\"_blank\" role=\"button\" rel=\"noopener noreferrer\">\n\t\t\t\t\t1. Click Here to view presentation (PDF)\n\t<\/a>\n\n\n\n<p><\/p>\n<\/div><!-- .vgblk-rw-wrapper -->","protected":false},"excerpt":{"rendered":"<p>Dr. Christa Noehammer Senior Scientist at AIT (Austrian Institute of Technology) Christa Noehammer works as Senior Scientist at the Austrian Institute of Technology where she has been heading the Molecular Medicine research unit for several years. Holding a master degree in Microbiology and a PhD in Biochemistry she has been working in the microarray field&#8230;<\/p>\n","protected":false},"author":1,"featured_media":35121,"parent":34845,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":""},"class_list":["post-35120","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Christa Noehammer &#8226; BioTech Pharma Summit<\/title>\n<meta name=\"description\" content=\"Christa Noehammer works as Senior Scientist at the Austrian Institute of Technology where she has been heading the Molecular Medicine research unit for several years.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.biotechpharmasummit.com\/index.php\/cdx-biomarkers-biobanking-2021-speakers\/christa-noehammer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Christa Noehammer &#8226; 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